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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC1
All Species:
10.61
Human Site:
Y590
Identified Species:
21.21
UniProt:
P35251
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35251
NP_002904.3
1148
128255
Y590
N
L
L
W
V
D
K
Y
K
P
T
S
L
K
T
Chimpanzee
Pan troglodytes
XP_001140765
1148
128250
Y590
N
L
L
W
V
D
K
Y
K
P
T
S
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001091287
1148
128475
Y590
N
L
L
W
V
D
K
Y
K
P
T
S
L
K
T
Dog
Lupus familis
XP_536259
1145
128125
K587
E
N
L
L
W
V
D
K
Y
K
P
T
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P35601
1131
125967
G587
K
N
I
I
G
Q
Q
G
D
Q
S
C
A
N
K
Rat
Rattus norvegicus
NP_445999
1131
125770
G585
K
N
I
I
G
Q
Q
G
D
Q
S
C
A
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512744
1233
136122
P673
L
W
V
D
K
Y
K
P
T
S
L
K
T
I
I
Chicken
Gallus gallus
NP_001006456
1147
128454
K587
E
T
L
L
W
V
D
K
Y
K
P
V
S
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35600
986
108596
S486
F
Y
K
A
A
L
L
S
G
P
P
G
I
G
K
Honey Bee
Apis mellifera
XP_397246
911
103001
F411
T
K
N
S
D
G
A
F
F
K
A
A
L
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797949
906
99249
T406
P
P
G
V
G
K
T
T
T
A
T
L
V
C
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38630
861
94885
T361
P
P
G
I
G
K
T
T
A
A
H
L
V
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
89.3
N.A.
82.4
81.3
N.A.
67.4
68.9
N.A.
N.A.
N.A.
39.9
36.2
N.A.
38
Protein Similarity:
100
99.6
98.5
93.7
N.A.
89.5
88.5
N.A.
77.2
79.6
N.A.
N.A.
N.A.
55.9
53.6
N.A.
52.2
P-Site Identity:
100
100
100
6.6
N.A.
0
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
20
20
N.A.
13.3
6.6
N.A.
N.A.
N.A.
13.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
9
0
9
17
9
9
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
17
0
9
0
% C
% Asp:
0
0
0
9
9
25
17
0
17
0
0
0
0
0
0
% D
% Glu:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
34
9
0
17
9
0
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
17
25
0
0
0
0
0
0
0
0
9
9
9
% I
% Lys:
17
9
9
0
9
17
34
17
25
25
0
9
0
25
42
% K
% Leu:
9
25
42
17
0
9
9
0
0
0
9
17
34
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
25
9
0
0
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
17
17
0
0
0
0
0
9
0
34
25
0
0
0
0
% P
% Gln:
0
0
0
0
0
17
17
0
0
17
0
0
0
0
17
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
0
9
0
9
17
25
17
0
9
% S
% Thr:
9
9
0
0
0
0
17
17
17
0
34
9
9
0
25
% T
% Val:
0
0
9
9
25
17
0
0
0
0
0
9
17
0
0
% V
% Trp:
0
9
0
25
17
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
25
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _